Tracking Bowel Cancer in a Vial of Blood: Clinical Applications of Circulating Tumour DNA
Walter and Eliza Hall Institute
1g Royal Parade, Parkville
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Associate Professor Jeanne Tie's research interests include the clinical applications of liquid biopsies in colorectal cancer, particularly the potential clinical utility of circulating tumor DNA in early stage disease. Supported by the Victorian Cancer Agency Research Fellowship, and in collaboration with Bert Vogelstein’s Lab at the Ludwig Center, Johns Hopkins, her group has initiated over 10 prospective multi-centre circulating tumor DNA biomarker studies. Her group’s recent work Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer, published in Science Translational Medicine, has been selected by the American Society of Clinical Oncology as one of the year’s major achievements in clinical cancer research and care.