Generating Human Kidney Tissue From Stem Cells


Generating Human Kidney Tissue From Stem Cells

Davis Auditorium
Walter and Eliza Hall Institute

1g Royal Parade, Parkville

Booking not required

Further Details

T: (03) 9345 2555

The generation of complex tissue organoids via directed differentiation of human pluripotent stem cells brings the prospect of personalised drug testing, disease modelling and regenerative medicine. We have developed a protocol for the generation of kidney organoids comprised of nephrons, collecting duct, vasculature and surrounding interstitium (Takasato et al, Nature, 2015) from human pluripotent stem cells. This protocol relies upon the stepwise recapitulation of morphogenetic events previously characterised during normal kidney development in the mouse. In this seminar, the application of such kidney organoids for disease modelling, drug screening, cell therapy and bioengineering applications will be presented.

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