Associate Professor Crook is one of the pioneers of in vitro disease modeling using stem cells. His team was the first to develop human stem cell-based models of psychiatric disorders. Earlier work by Jeremy includes deriving the world’s first clinically compliant human embryonic stem (hES) cell lines for drug discovery and cell-based therapies. The lines have recently been selected by the Californian Institute of Regenerative Medicine (CIRM) and University of California System (UC-system) institutions to streamline their efforts to translate pluripotent stem cells to human therapies. Associate Professor Crook’s stem cell research is complimented by his work with the International Stem Cell Banking Initiative (ISCBI). ISCBI’s purpose is to support a global network of stem cell banks and provide international standards for banking, characterization, and testing hES and induced pluripotent stem (iPS) cells for research and clinical cell delivery.
Other noteworthy achievements by Associate Professor Crook include working with thought leaders in the field to develop a standard nomenclature for hES and iPS cell lines and a minimum set of criteria for reporting new cell lines, endorsed by the International Stem Cell Forum (ISCF). Jeremy’s work has been published extensively in high impact journals such as Cell Stem Cell, Nature Biotechnology, Nature Cell Biology, Nature Genetics, Nature Molecular Psychiatry and Proceedings of the National Academy of Sciences. Finally, Associate Professor Crook is serving on the editorial boards of many scientific journals and advisory panels, including the International Stem Cell Registry (ISCR). The ISCR is a component of the University of Massachusetts Human Stem Cell bank and Registry, is developed in partnership with and funded by the Massachusetts Life Sciences Center, the Harvard Stem Cell Institute and the Stem Cell Task Force at the National Institutes of Health.
Jeremy was awarded a PhD in 1998, completed in the Department of Pathology at The University of Melbourne. Jeremy holds concurrent appointments as Head of the Stem Cells and Disease Models Laboratory at the Centre for Neural Engineering, The University of Melbourne, Associate Professor and Principal Fellow in the Department of Surgery – St Vincent’s Hospital, The University of Melbourne, and Principal Researcher in the Optics and Nanoelectronics Research Group of the National ICT Australia Victorian Research Laboratory. Jeremy previously worked as Director of Stem Cell Medicine at the O’Brien Institute in Melbourne, was the Senior Research Scientist and Group Leader of the Stem Cell Disease Models Laboratory at A*STAR's Institute of Medical Biology in Singapore, the Head of the Singapore Stem Cell Bank (SSCB), and a research fellow in the US National Institutes of Health Clinical Brain Disorders Branch of the National Institute of Mental Health. In the biotechnology sector Jeremy has worked for ES Cell International (ESI) where he was Program Manager of Platform Technologies in Melbourne and Singapore, and is the Founding Director of the stem cell start-up Cytentia Pty Ltd.